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How I knew when to start backing Novo Nordisk’s biggest rival instead

The Danish firm’s complacency is its undoing in the weight-loss drug war

    • Novo Nordisk has gone from being Europe’s most valuable listed company to losing more than US$300 billion in market value.
    • Novo Nordisk has gone from being Europe’s most valuable listed company to losing more than US$300 billion in market value. PHOTO: REUTERS
    Joyce Hooi
    Published Thu, Oct 30, 2025 · 07:00 AM

    THE folks in Danish drugmaker Novo Nordisk’s orbit seem awfully easy to catch off-guard. When its then chief executive officer Lars Fruergaard Jorgensen was ousted in May, you could have knocked industry analysts over with a feather. Jorgensen himself reportedly had not seen his own sacking coming.

    Last week, the beleaguered pharmaceutical giant raised yet more eyebrows with news of its massive board overhaul – all six of its independent directors, as well as its board chair, are to step down, following a disagreement with its controlling shareholder over the firm’s future.

    I was surprised, too – surprised that this corporate spring-cleaning hadn’t happened sooner.

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