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Singapore-listed iX Biopharma bets big on non-opioid pain relief

Its flagship drug Wafermine is a sublingual ketamine wafer that delivers rapid pain relief without addiction risks

Tessa Oh
Published Mon, Apr 13, 2026 · 07:00 AM
    • Eva Tan, chief commercial officer, and Eddy Lee,  chairman and chief executive officer of IX Biopharma; the company wants to lead the world in longevity
    • Eva Tan, chief commercial officer, and Eddy Lee, chairman and chief executive officer of IX Biopharma; the company wants to lead the world in longevity PHOTO: TAY CHU YI, BT

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    [SINGAPORE] It took semaglutide (an anti-diabetic prescription drug that is gaining traction as an anti-obesity medication) to convince Wall Street that an overlooked drug class could become a hundred-billion-dollar market. Now, a handful of companies are betting that non-opioid pain relief is next – and Singapore’s iX Biopharma thinks it has the edge.

    The company’s flagship drug, Wafermine, is a sublingual ketamine wafer designed to dissolve under the tongue and deliver rapid pain relief without the addiction risks that have made opioids so controversial.

    Since its listing on the Singapore Exchange (SGX) in 2015, iX Biopharma has been developing Wafermine through the clinical trial process required for regulatory approval.

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